Investigating the Rate of Group B Streptococcus in Below 3 Months Year Old Infants with Sepsis Clinical Symptoms Hospitalized in Ghaem Hospital of Mashhad

Document Type: Original Article

Authors

1 Neonatal research center, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Neonatal research center, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Pediatrician, Faculty of medicine, Mashhad University of Medi cal Sciences, Mashhad, Iran.

4 Microbiologist, Department of microbiology, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

5 Neonatal research center, Mashhad University of Medical Sciences, Mashhad, Iran.

Abstract

Introduction Group B streptococcus is the main reason of neonatal infection in developed countries and causes a widespread clinical indications. In developing countries such as Iran, its rate of appearance is not determined. With regard to colonization and the relative high epithelia of group B streptococcus, it is likely that the incidence of group B streptococcus in neonatal sepsis is so high.In the present study, we attempted to use the molecular methods to identify this bacterium and develop the culture environments as well.
Methods In the present study, a hundred below three months year old infants with sepsis hospitalized in ICU sector of Ghaem hospital for one year were studied since Khordad 1388 (June 2010). After getting consent from the infants’ parents, three blood samples of these patients in the sterile container with lid were transferred to the laboratory (two samples for culturing in normal environment and the other for PRC). All of the information was filled out by doctors in the incidence. SPSS 11.5 and descriptive-analytic tests were used for data analysis.
Results With regard to the high rate of anti-biotic consumption by mothers before delivery, it is necessary to use more sensitive methods like PCR to identify the Group B Streptococcus.
Conclusion Acceptable results and a growing survival rate was observed in this series of patients and we hope better results with improvements in  minimally invasive methods.

Keywords


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