Is Garlic Necklace Effective in the Treatment of Neonatal Jaundice

Document Type : Original Article

Authors

1 University of KUFA- College of Medicines, Pediatrics Department

2 Jabir ibnHayyan Medical University, College of Medicine, Department of Gynecology and Obstetrics

Abstract

Background: Hyperbilirubinemia is a prevalent clinical problem which affects 60% of term and 80% of preterm neonates. Garlic is the most well-known remedy used in Iraq for the treatment of jaundice. To test the effectiveness of garlic necklace in the treatment of neonatal jaundice.
Methods: This cohort study was conducted in the neonatal intensive care unit (NICU) of Al Zahraa Teaching Hospital within January-November 2016. A total number of 110 neonates were included in the present study out of whom 36 neonates were allocated to the test group and 74 newborns were assigned to the control group. The neonates in both groups received the common treatment of jaundice, according to guidelines adopted in our hospital. Nonetheless, the neonates in the test group wear a seven-clove garlic necklace till discharge, in addition to the common treatment. We compared the two groups regarding the length of hospital stay and the rate of total serum bilirubin (TSB) decline.
Results: As illustrated by the obtained results, a significant reduction was detected in the hours of hospitalization in the control group, as compared to the test group (P= 0.006).
A significant reduction was observed in hours of hospitalization in the control group, as compared to the test group (P=0.006) suggesting the harmful effect of garlic on neonatal jaundice. This can be attributed to the long-time dependence of patients' families on garlic as a sole treatment before seeking medical help. Nonetheless, this treatment made jaundice worse needing prolonged phototherapy. The rate of decline in TSB in hospitalized patients was comparable in both groups (P= 85). This again suggests that garlic has no beneficial effect on the treatment of neonatal jaundice.
Conclusion: Based on the results of the present study, garlic has no effect on the treatment of neonatal jaundice, rather it may cause prolonged phototherapy and hospital stay.

Keywords


1. Maheshwari A, Carlo WA. Digestive system disorders. In: Kliegman RM, Stanton BF, St Geme JW III, Schor NF, editors. Nelson textbook of pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2015. P. 102. 2. Maisels MJ. Neonatal jaundice. Pediatr Rev. 2006; 27(12):443. 3. Moerschel SK, Cianciaruso LB, Tracy LR. A practical approach to neonatal jaundice. Am Fam Phys. 2008; 77(9):1255-62. 4. Bhutani VK, Donn SM, Johnson LH. Risk management of severe neonatal hyperbilirubinemia to prevent kernicterus. Clin Perinatol. 2005; 32(1):125-39. 5. Oski FA. Differential diagnosis of jaundice. In: Taeusch HW, Ballard RA, Avery MA, editors. Schaffer and Avery’s diseases of the newborn. 6th ed. Philadelphia: WB Saunders; 1991. 6. American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. Management of hyperbiliru-binemia in the newborn infant 35 or more weeks of gestation. Pediatrics. 2004; 114(1):297. 7. Sultan AS. Medicine in the 21st century: the situation in a rural Iraqi community. Patient Educ Counsel. 2007; 68(1):66-9.