Determination of Neonatal Prognosis Based on Umbilical Vein Blood Gas in Hakim Hospital of Neyshabur, Iran during 2017-2018

Document Type : Original Article

Authors

1 Department of Pediatrics, Hakim Hospital, Neyshabur University of Medical Sciences, Neyshabur, Iran

2 Department of Midwifery, Neyshabur University of Medical Sciences, Neyshabur, Iran

3 Student Research Commitee School Of Paramedicine, Mashhad Branch, Islamic Azad University, Mashhad, Iran

4 Department of Neonatal Intensive Care, Neyshabur University of Medical Sciences, Neyshabur, Iran

Abstract

Background: In order to determine the prognosis of neonates, it is recommended to use umbilical gas analysis in all high-risk pregnancies. However, utilizing umbilical gas analysis and Apgar score together is very helpful for determining the mortality rate confidence interval. Therefore, in this study, we investigated the application of umbilical gas analysis in assessing the prognosis of infants.
Methods: This cross-sectional study was conducted in Hakim Hospital of Neyshabur, Iran during 2017-2018 with 100 subjects in each group of control and test. Blood samples were collected from the umbilical vein of all neonates. The data were compared between the two groups by the t-test and Mann-Whitney test using the SPSS software version 18 at the significance level of P ≤ 0.05.
Results: Our findings demonstrated that both hospitalization and the need for resuscitation had significant relationships with pH and base excess (BE) in the case and control groups (P<0.05). Moreover, 52.7% of the subjects in the intervention group and 47.3% of the participants in the control group were born through cesarean section. Therefore, the two groups were not significantly different regarding the route of delivery (P>0.05)
Conclusion: According to the results of this study, a positive relationship was found between the neonatal prognosis and umbilical vein blood gas. Consequently, we can determine neonatal prognosis based on umbilical vein blood gas.

Keywords

References

1. Volpe JJ. Perinatal brain injury: From pathogenesis to neuroprotection. Ment Retard Dev Disabil Res Rev. 2001; 7(1):56-64.
2. Low JA, Pickersgill H, Killen H, Derrick EJ. The prediction and prevention of intrapartum fetal asphyxia in term pregnancies. Am J Obstet Gynecol. 2001; 184(4):724-30.
3. Anceschi MM, Piazze JJ, Vozzi G, Ruozi Berretta A, Figliolini C, Vigna R, et al. Antepartum computerized CTG and neonatal acid-base status at birth. Int J Gynaecol Obstet. 1999; 65(3):267-72.
4. Thomas F, Blumen IJ. Assessing oxygenation in the transport environment. Air Med J. 1999; 18(2):79-86.
5. Armstrong L, Stenson BJ. Use of umbilical cord blood gas analysis in the assessment of the newborn. Arch Dis Child Fetal Neonatal Ed. 2007; 92(6):F430-4.
6. Boskabadi H, Ashrafzadeh F, Doosti H, Zakerihamidi M. Assessment of risk factors and prognosis in asphyxiated infants. Iran J Pediatr. 2015; 25(4):e2006.
7. Rahimi R, Akbarianrad Z, Zahed Pasha Y. The effect of mode of delivery on the umbilical artery pH. Caspian J Pediatr. 2016; 2(1):113-7.
8. Hendrix NW, Chauhan SP, Runzel AR, Counts SL, Magann EF. Remote umbilical arterial blood gas analysis: experience at two community hospitals. J Matern Fetal Investig. 1997; 7(4):180-3.
9. Ahmadpour-Kacho M, Asnafi N, Javadian M, Hajiahmadi M, Taleghani N. Correlation between Umbilical cord pH and apgar score in high-risk pregnancy. Iran J Pediatr. 2010; 20(4):401-6.
10. Goldaber KG, Gilstrap LC 3rd, Leveno KJ, Dax JS, McIntire DD. Pathologic fetal acidemia. Obstet Gynecol. 1991; 78(6):1103-7.
11. Carluccio A, Contri A, Gloria A, Veronesi MC, Sfirro
MP, Parrillo S, et al. Correlation between some arterial and venous blood gas parameters in healthy newborn Martina Franca donkey foals from birth to 96 hours of age. Theriogenology. 2017; 87:173-8.
12. Vassalo FG, Simões CR, Sudano MJ, Prestes NC, Lopes MD, Chiacchio SB, et al. Topics in the routine assessment of newborn puppy viability. Top Companion Anim Med. 2015; 30(1):16-21.
13. Irles C, González-Pérez G, Carrera Muiños S, Michel Macias C, Sánchez Gómez C, Martínez-Zepeda A, et al. Estimation of neonatal intestinal perforation associated with necrotizing enterocolitis by machine learning reveals new key factors. Int J Environ Res Public Health. 2018; 15(11):E2509.
14. Zanardo V, de Luca F, Simbi AK, Parotto M, Guerrini P, Straface G. Umbilical cord blood acid-base analysis and the development of significant hyperbilirubinemia in near-term and term newborns: a cohort study. Ital J Pediatr. 2017; 43(1):67.
Iranian Journal of Neonatology
Volume 11, Issue 2
May 2020
Pages 30-34

Files

Share

How to cite

Statistics