Background: Neonatal jaundice is yellow discoloration of a newborn baby's skin and eyes, caused because the baby’s blood contains an excess of bilirubin, a yellow pigment of red blood cells. It is a leading cause of hospitalization in the first week of life worldwide. If inappropriately managed, it could result in significant bilirubin-induced mortality and disability. Methods: This study was carried out at the Neonatal Intensive Care Unit (NICU) of The Federal Medical Centre, Asaba, Delta State, Nigeria. A descriptive retrospective research design was used for the study and a sample of 100 neonates was selected using a stratified random sampling method. Data were collected from the medical records of all neonates admitted for neonatal jaundice within the period of study. Data collected was analyzed using tables, frequency, and percentage. Results: Findings from the study revealed that there is a high incidence of neonatal jaundice among neonates admitted into the neonatal intensive care unit as indicated by 100 (40%). Of this percentage, females admitted (50.4%) had neonatal jaundice more than their male counterparts (49.6%). The study also revealed that the jaundice is caused due to poor breastfeeding 28 (28%), followed by premature birth 20 (20%), infection 15 (15%), Severe Anaemia 12 (12%), ABO incompatibility, 10 (10%), Idiopathic 10 (10%), and others 5%. Neonatal jaundice due to fever was not recorded in the study 0 0%. The types/variant of the jaundice is as follows; breastfeeding jaundice 42%, physiological jaundice 36% and other forms of jaundice 22%. Conclusion/Recommendation: Incidence of Neonatal Jaundice is high the community, affecting male and female neonates equally. The jaundice is predominantly breastfeeding and physiological jaundice. It is recommended among other things that programs that will enhance proper education of the public/parents on the impact of breastfeeding on neonatal jaundice be promoted by the government and health workers