Iranian Journal of Neonatology

Iranian Journal of Neonatology

Case-report of a Neonate with COVID-19 Infection: How he Has been Infected?

Document Type : Case Report

Authors
Javad Nazari 1
Zahra-Sadat Mousavi 2
Hasan Taher-Ahmadi 1
Maryam Shokrpour 3
Afsane Akhonzade 1
Pezhman Hadadi 4
Mojtaba Didehdar 5
1 Department of Pediatrics, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran
2 Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran
3 Department of Gynecology and Obstetrics, School of Medicine, Endocrinology and Metabolism Research Center, Arak University of Medical Sciences, Arak, Iran
4 Taleghani Hospital, Arak University of Medical Sciences, Arak, Iran
5 Department of Medical Parasitology and Mycology, School of Medicine, Arak University of Medical Sciences, Arak, Iran
10.22038/ijn.2021.53152.1964
Abstract
Background: It has been indicated that pregnant women and neonates are susceptible to COVID‐19 infection. Nevertheless, the unresolved question is about the possibility of COVID‐19 infection in neonates born to COVID‐19 mothers. The present study aimed to assess the routes through which neonates may be infected with the virus: vertically or nosocomially.
Case report:This study reports the case of a neonate with COVID-19 infection who became symptomatic 30 h after birth. His pharyngeal swab specimen was reported as positive by real-time reverse transcription-polymerase chain reaction (RT-PCR). It happened while the newborn’s mother was tested for the COVID-19 twice, and she received negative results both times.
Conclusion:According to the incubation period of COVID‐19 which is at least 1 day, the possibility of nosocomial transmission is less than other cases reported so far. Moreover, the mother had no COVID-19 symptoms during the last month of delivery. Further clinical research is necessary to determine the routes of maternal transmission of COVID-19 to neonates.
 
 
Keywords
COVID‐19
Neonate
Nosocomial infection
Vertical transmission
  1. Bonilla-Aldana DK, Villamil-Gómez WE, Rabaan AA, Rodríguez-Morales AJ. A new viral zoonosis of global concern. Iatreia. 2020; 33(2):107-10.
  2. Dong Y, Mo XI, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China. Pediatrics. 2020; 145(6):e20200702.
  3. Takahashi N, Kitajima H, Kusuda S, Morioka I, Itabashi K. Pandemic (H1N1) 2009 in neonates, Japan. Emerg Infect Dis. 2011; 17(9):1763-5.
  4. Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W, et al. Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases. Radiology. 2020; 296(2):E32-40.
  5. Fang Y, Zhang H, Xie J, Lin M, Ying L, Pang P, et al. Sensitivity of chest CT for COVID-19: comparison to RT-PCR. Radiology. 2020; 296(2):E115-7.
  6. Luo L, Liu D, Liao XL, Wu XB, Jing QL, Zheng JZ, et al. Modes of contact and risk of transmission in covid-19: a prospective cohort study 4950 close contact persons in guangzhou of China. Lancet. 2020; In Press.
  7. Corman VM, Landt O, Kaiser M, Molenkamp R, Meijer A, Chu DK, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 2020; 25(3):2000045.
  8. Lauer SA, Grantz KH, Bi Q, Jones FK, Zheng Q, Meredith HR, et al. The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application. Ann Intern Med. 2020; 172(9):577-82.
  9. Schwartz DA, Graham AL. Potential maternal and infant outcomes from (Wuhan) coronavirus 2019-nCoV infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses. 2020; 12(2):194.

10. Amini S, Koolivand A, Nazari J. Managerial challenges and solutions for COVID-19 outbreak: New insights for global primary healthcare system. Ethics Med Public Health. 2020; 15:100567.

11. Koolivand A, Amini S. The importance of PHC-based measures in controlling COVID-19 outbreak: Implications for global health system. Ethics Med Public Health. 2020; 14:100549.

 

 


 

Iranian Journal of Neonatology
Volume 12, Issue 3
Summer 2021
Pages 104-109