Isolated Right Ventricular Non-compaction in a Neonate Born to a Mother with Gestational Diabetes: A Case Report

Document Type : Case Report

Authors

1 Amir Kabir Hospital, Arak University of Medical Sciences, Arak, Iran

2 Department of Emergency, School of Medicine, Arak University of Medical Sciences, Arak, Iran

3 Department of Pediatrics, School of Medicine, Amir Kabir Hospital, Arak University of Medical Sciences, Arak, Iran

Abstract

Background: Ventricular non-compaction, which is a rare congenital cardiomyopathy, results from an arrest in normal endomyocardial embryogenesis. It is characterized by a pattern of prominent trabecular meshwork and deep inter-trabecular recesses. The clinical manifestations include systolic and diastolic dysfunctions, heart failure, ventricular arrhythmias, and cardioembolic events.
Case report: Here we present the case of a neonate (38 weeks, weighing 2580 gr) born to a mother with gestational diabetes (GDM) with isolated right ventricular non-compaction (IRVNC) and systolic and diastolic right heart dysfunction due to meconium aspiration syndrome and tension pneumothorax. A 4-month follow-up demonstrated a complete improvement in the newborn.
Conclusion: It is of paramount importance to consider RVNC cardiomyopathy a differential diagnosis of cyanosis and respiratory distress due to meconium aspiration syndrome in neonate s born to mothers with GDM. Apart from RV cardiac dysfunction, RVNC could cause such complications as pulmonary hypertension and tension pneumothorax. It can be also spontaneously improved in GMD.

Keywords

References

1. Maron BJ, Towbin JA, Thiene G, Antzelevitch C, Corrado D, Arnett D, et al. Contemporary definitions and classification of the cardiomyopathies: an American heart association scientific statement from the council on clinical cardiology, heart failure and transplantation committee; quality of care and outcomes research and functional genomics and translational biology interdisciplinary working groups; and council on epidemiology and prevention. Circulation. 2006; 113(14):1807-16.
2. Weiford BC, Subbarao VD, Mulhern KM. Noncompaction of the ventricular myocardium. Circulation. 2004; 109(24):2965-71.
3. Kaur J, Aziz BB, Jaafar R. Isolated right ventricular non-compaction in a newborn. Progress Pediatr 
Cardiol. 2019; 52:57-9.
4. Maheshwari M, Gokroo RK, Kaushik SK. Isolated non-compacted right ventricular myocardium. J Assoc Physicians India. 2012; 60:56-7.
5. Saglam M, Saygin H, Kozan H, Ozturk E, Mutlu H. Noncompaction of ventricular myocardium involving the right ventricle. Korean Circ J. 2015; 45(5):439-41.
6. Aggarwal S, Kalavakunta J, Gupta V. A case of isolated right ventricle noncompaction with ST-Elevation chest leads. Heart Views. 2016; 17(1):30-4.
7. Boughrarou R, Mansouri B. Noncompaction of ventricular myocardium: a magnetic resonance imaging study of 50 patients. Eur Soc Radiol. 2016; 10:C-0430.
8. Markiewicz-Loskot G, Moric-Janiszewska E, Loskot M, Szydlowski L, Weglarz L, Hollek A. Isolated ventricular non-compaction: clinical study and genetic review. Europace. 2006; 8(12):1064-7.
9. Yun H, Zeng MS, Jin H, Yang S. Isolated noncompaction of ventricular myocardium: a magnetic resonance imaging study of 11 patients. Korean J Radiol. 2011; 12(6):686-92.
10. Fazio G, Lunetta M, Grassedonio E, Gullotti A, Ferro G, Bacarella D, et al. Noncompaction of the right
ventricle. Pediatr Cardiol. 2010; 31(4):576-8.
11. Jenni R, Oechslin E, Schneider J, Attenhofer Jost C, Kaufmann PA. Echocardiographic and pathoanatomical characteristics of isolated left ventricular non-compaction: a step towards classification as a distinct cardiomyopathy. Heart. 2001; 86(6):666-71.
12. Lim S, Ahn J, Lee D, Park M. Isolated right ventricular noncompaction accompanied by right ventricular failure. Korean J Med. 2015; 88(1):69-73.
Iranian Journal of Neonatology
Volume 11, Issue 4
October 2020
Pages 114-118

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