Prevalence of CH that identified in neonatal screening program in Mashhad health center 2011

Document Type : Original Article



Introduction: Congenital hypothyroidism is the most common endocrine disease and is a major cause of preventable mental retardation. In most cases, it seems quite natural born at birth with delayed diagnosis, complications will cause irreparable brain. Now almost all industrialized countries and many developing countries the newborn screening program to systematically do. Khorasan Province neonatal hypothyroidism screening using TSH measurements are taken from the heel onto filter paper from the year 2006.
Methods: This study is a retrospective study of neonatal screening results are. In a thyroid screening program to inform all mothers through health centers in 3 to 5 days of birth, blood samples on filter paper obtained their heels and the TSH is measured in this study, the results of the 2011 cases were analyzed.
Results: Newborn screening of 24,703 cases in 2011, 52% of the infants was girls and 48% boys. Samples in 3 to 5 days, and 30% of the time for various reasons, was later scheduled the 96.9% of normal results (i.e. TSH less than 5), and 3% were suspected (i.e., 5 to 20) and 0.01% positive (i.e. more than 20) have been reported. In positive tests for suspected cases of 4% and a total of 1.3 in a thousand babies have been born with hypothyroidism that the statistics of the prevalence of hypothyroidism (1 in 5000 births) is more.
Conclusions: congenital hypothyroidism incidence in the study population in the province 1.3 that the results obtained in births is lower than the national rate (1.7 in a thousand births) is.