Herpes simplex virus type 2: Seroprevalence in pregnant women

Document Type : Original Article



Introduction: Herpes Simplex Virus type 2 (HSV-2)  is a highly prevalent sexually transmitted infection (STI) The prevalence of HSV-2 infection is increasing in many populations and geographic areas . Herpes simplex virus type 2 (HSV-2) is the cause of most genital herpes and is almost always sexually transmitted. Most HSV-2 infections are consequently expected to occur after the onset of sexual activity. Genital herpes is a cause of morbidity and increases the risk of HIV acquisition, due to disruption of mucosal membranes. Data on prevalence of herpes simplex virus type 2 (HSV-2) infections are limited in Asia
Methods: Our study focuses on seroepidemiology of HSV-2 infection among pregnant women in Urmia-West Azerbaijan to estimate the regional Seroprevalence of anti HSV-2 antibody in Urmia and to investigate the possible correlation of seropositivity with abortion history.
Results:  This study was conducted on 86 randomly selected pregnant women. ELISA was performed to detect anti HSV-2 IgG antibody. Detailed history and questionnaire filled. Of the 86 cases screened for anti HSV-2 IgG antibodies, 5 (5.81%) tested positive.
 Conclusions: These results may have public health importance for our country as the high rate of HSV-2 infection and be useful for designing strategies for focusing prevention efforts for HSV-2 infection