%0 Journal Article %T Severe Persistant Cyanosis in a Newborn Due to Prominent Eustachian Valve %J Iranian Journal of Neonatology %I Mashhad University of Medical Sciences %Z 2251-7510 %A Dogan, Vehbi %A Ertuğrul, İlker %A Kayalı, Şeyma %A Koyuncu, Ece %A Arman Örün, Utku %A Karademir, Selmin %D 2017 %\ 03/01/2017 %V 8 %N 1 %P 37-39 %! Severe Persistant Cyanosis in a Newborn Due to Prominent Eustachian Valve %K Cyanosis %K Chiari network %K Eustachian valve %K Newborn %K Sildenafil %R 10.22038/ijn.2017.16289.1184 %X ABSTRACTThe valves of right horn of systemic venous sinus are prominent structures within the right atrium during early embryonic period. Involution of these structures may not be complete, resulting in a spectrum of anatomical presentations such as cyanosis. A full-term male neonate referred to our hospital for precise evaluation of severe cyanosis on the first day of life. Echocardiographic examination revealed right-to-left interatrial shunting through patent foramen ovale due to prominent eustachian valve with normal estimated right heart pressures from peak tricuspid regurgitation velocity. He was maintained with supplemental oxygen and a PDE-5 inhibitor (sildenafil) and subsequently improvement in oxygen saturation was achieved. The patient was discharged after 2 weeks of treatment. In conclusion; the embryologic remmants of the sinus venosus rarely may lead to right-to-left shunting resulting in severe cyanosis. Pulmonary vasodilators such as sildenafil may improve oxygen saturation in these patients even in case of normal right heart pressures. %U https://ijn.mums.ac.ir/article_8521_239c6773df221aa66f0db52f67fede85.pdf