@article { author = {Akbarian_Rad, Zahra and Zahedpasha, Yadollah and Ahmadpour-Kacho, Mousa and Rajabnia, Ramazan and Tohidi, Fatemeh Tohidi}, title = {Intestinal Lactobacillus Species: Is it Equal in Colicky and non-Colicky Breastfed Infants?}, journal = {Iranian Journal of Neonatology}, volume = {4}, number = {2}, pages = {1-4}, year = {2013}, publisher = {Mashhad University of Medical Sciences}, issn = {2251-7510}, eissn = {2322-2158}, doi = {10.22038/ijn.2013.1074}, abstract = {Introduction: Infantile colic is one of the most common problems in the family in few weeks after birth. Pathophysiology of colic has not been explained yet. The aim of this study was to compare the intestinal microflora in colicky and non-colicky infants. Materials and Methods: Seventy breastfed infant aged 15-60 days were enrolled in this study and divided into two groups of 35 colicky and non-colicky according to Wessel’s criteria. Stool sample were cultured on selective media. Lactobacillus species were defined by specific tests. Difference in the normal flora between two groups was analyzed by SPSS 16, t-test and a P-value less than 0.05 was considered being significant. Results: Among 35 colicky and non-colicky infant, 15 and 20 culture positive lactobacilli were detected respectively. Lactobacillus (LB) acidophilus grew in 7 (20%) non-colicky infants and none of colicky infants. (P=0.02). Conclusion: Absence of LB acidophilus in colicky infants may predispose growth of other bacteria which may play a role in the pathogenesis of colic and its symptoms.}, keywords = {Infantile colic}, url = {https://ijn.mums.ac.ir/article_1074.html}, eprint = {https://ijn.mums.ac.ir/article_1074_c99ac52c1593298efe125fce9cc3eb34.pdf} }