Intestinal Lactobacillus Species: Is it Equal in Colicky and non-Colicky Breastfed Infants?
Zahra
Akbarian_Rad
Non-Communicable Pediatric Diseases Research Center, Faculty of Medicine,Babol University of Medical Sciences, Babol, Iran
author
Yadollah
Zahedpasha
Non-Communicable Pediatric Diseases Research Center, Faculty of Medicine,Babol University of Medical Sciences, Babol, Iran
author
Mousa
Ahmadpour-Kacho
Non-Communicable Pediatric Diseases Research Center, Faculty of Medicine,Babol University of Medical Sciences, Babol, Iran
author
Ramazan
Rajabnia
Department of Microbiology and Immunology, Faculty of Medicine ,Babol University of Medical Sciences, Babol, Iran
author
Fatemeh Tohidi
Tohidi
Department of Biotechnology, Faculty of Medicine ,Babol University of Medical Sciences, Babol, Iran
author
text
article
2013
eng
Introduction: Infantile colic is one of the most common problems in the family in few weeks after birth. Pathophysiology of colic has not been explained yet. The aim of this study was to compare the intestinal microflora in colicky and non-colicky infants. Materials and Methods: Seventy breastfed infant aged 15-60 days were enrolled in this study and divided into two groups of 35 colicky and non-colicky according to Wessel’s criteria. Stool sample were cultured on selective media. Lactobacillus species were defined by specific tests. Difference in the normal flora between two groups was analyzed by SPSS 16, t-test and a P-value less than 0.05 was considered being significant. Results: Among 35 colicky and non-colicky infant, 15 and 20 culture positive lactobacilli were detected respectively. Lactobacillus (LB) acidophilus grew in 7 (20%) non-colicky infants and none of colicky infants. (P=0.02). Conclusion: Absence of LB acidophilus in colicky infants may predispose growth of other bacteria which may play a role in the pathogenesis of colic and its symptoms.
Iranian Journal of Neonatology
Mashhad University of Medical Sciences
2251-7510
4
v.
2
no.
2013
1
4
https://ijn.mums.ac.ir/article_1074_c99ac52c1593298efe125fce9cc3eb34.pdf
dx.doi.org/10.22038/ijn.2013.1074
Surfactant Administration via Thin Catheter during Spontaneous Breathing: Randomized Controlled Trial in Alzahra hospital
Kayvan
Mirnia
Neonatologist, Pediatrics Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
author
Mohammad
Heidarzadeh
Assistant Prof. of Neonatology, Dept. of Pediatrics, Tabriz University of Medical Sciences, Director of Dept. of Neonatal Health, Ministry of Health & Medical Education, Tabriz ,Iran
author
Mohammad Bagher
Hoseini
Associated Prof. of Neonatology, Dept. of Pediatrics, Tabriz University of Medical Sciences, Tabriz, Iran
author
Alireza
Sadeghnia
Assistant prof. of Neonatology, Isfahan University of Medical Sciences, Isfahan, Iran
author
Forouzan
Akrami
Master of maternal and neonatal health science, Master of public Health (SDH), Dept. of Neonatal Health, Deputy of Public Health, Ministry of Health and Medical Education, Tehran, Iran
author
Masomeh
Balila
Assistant prof. of Neonatology, Boosher University of Medical Sciences, Boosher,Iran
author
Morteza
Ghojazadeh
PHD of Physiology, Tabriz University of Medical Sciences, Tabriz, Iran
author
Fatemeh
Shafai
MSC of NICU, Tabriz University of Medical Sciences, Tabriz, Iran
author
Fatemeh
Rezaei
MSC of NICU, Tabriz University of Medical Sciences, Tabriz, Iran
author
text
article
2013
eng
Introduction Respiratory distress syndrome (RDS) is a current cause of morbidity in premature infants resulted from surfactant deficiency. The primary aim of this randomized study was to describe the feasibility of early administration of surfactant via a thin catheter during spontaneous breathing (TEC) and compare its outcomes with the InSurE (Intubate, Surfactant, Extubate) procedure Materials and Methods Premature infants with RDS, who were ≤ 32 weeks old and stabilized with nasal continuous positive airway pressure (nCPAP), were randomized to receive surfactant either by the TEC or InSurE technique. Tracheal instillation of 200 mg/kg Curosorf via 5-F catheter during spontaneous breathing under nCPAP was performed in the intervention group (n=38). In the InSurE group (n=40), infants were intubated, received positive pressure ventilation for 30 seconds after surfactant instillation, and placed on nCPAP immediately Results Necrotizing enterocolitis rate was significantly lower in TEC group, than InSurE group, [p<0.02, RR=0.49, CI=%95(0.39_0.62)]. But rate of other morbidities did not significant difference between two groups. Although Mechanical ventilation duration did not significant different between two groups (p=0.2), but Total CPAP duration was shorter in TEC group, significantly [P<0.01, RR=8.2, CI=%95 (-37.9_-4.8)]. Need for O2 supplement and mean of total hospital duration was also lower in TEC group, but was not significant, statistically Conclusion The TEC technique is feasible for the treatment of respiratory distress syndrome in infants with very low birth weight and decreases total nCPAP duration, significantly. But Judgment of substitution TEC instead of InSurE as a routine technique need to more studies.
Iranian Journal of Neonatology
Mashhad University of Medical Sciences
2251-7510
4
v.
2
no.
2013
5
9
https://ijn.mums.ac.ir/article_1075_e243b8dc0ac71e2f01d50808e3bb4a2e.pdf
dx.doi.org/10.22038/ijn.2013.1075
Effects of Fumaria Extract on Colic Pain in 3-16 Weeks Infants
Sedigheh
Montaseri
Fatemeh (P.B.U.H) College of Nursing &Midwifery, Shiraz university of Medical sciences, Shiraz, Iran
author
Shahnaz
Pourarian
Neonatal Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
author
Hashem
Montaseri
Department of Pharmaceutics, Faculty of Pharmacy, Shiraz University of Medical Sciences,
Shiraz, Iran
author
text
article
2013
eng
Introduction Infantile colic is somehow believed to be the worst pain a baby has thus experienced. It is usually manifested as an acute abdominal pain with intense spasmodic cramping accompanied by intense crying lasting for more than 3 hours a day during at least a three days period. Accordingly, this study is aimed to investigate the effects of Fumaria on such pain in 3-16 weeks-old infants. Materials and Methods A double-blind clinical trial has been conducted on 60 newborns. The cases were selected through simple random sampling and divided into two groups, namely control and treatment group and given 2.5cc placebo or Fumaria extract. Daily symptoms were gathered and recorded via a specially designed questionnaire. Chi-squared test was used to analyze the mustered data. Results Out of the 60 cases, 50 newborns completely participated in the study. This study revealed a significant difference between the two aforementioned study groups as regards to the length and frequency of crying periods and the number of times an infant would wake up due to colic pain (P<0.05). Concerning the demographic characteristics, there was no statistically significant difference between the control and the treatment group (p>0.05) . Conclusion It was revealed that Fumaria extract is of great help in reducing the colic pain in 3-16 week-old infants.
Iranian Journal of Neonatology
Mashhad University of Medical Sciences
2251-7510
4
v.
2
no.
2013
10
15
https://ijn.mums.ac.ir/article_1076_2d16d0586b127a7b5d0ca4940a40c228.pdf
dx.doi.org/10.22038/ijn.2013.1076
Promotion of Family-Centered Care in Neonates Hospitalized in the NICU based on Health Belief Model
Atefeh
Estiri
Bs in Nursing, Quaem Medical Center, NICU ward
author
Hamidreza
Zendehtalab
MSc in Community Health Nursing, Faculty member, School of Nursing and Midwifery, Mashhad University of medicine, Mashhad, Iran.
author
text
article
2013
eng
Introduction The family is in a crisis and a stressful experience when neonate is admitted in NICU ward. In recent decades, role of family in the care of neonates has completely changed. Now, empowerment of families in the care of neonates hospitalized is an important approach in the field of neonatal nursing . Therefore, it is necessary for parents, especially mothers with neonates in NICU ward that be done nursing professional supports. Materials and Methods This quasi-experimental study was conducted in Mashhad, Qaem Medical Center, in 2011, using before and after design. In this study, 34 women aged 19-41 years were participated voluntarily who had hospitalized neonate in the NICU ward, from June to October 2011. In order to find subjects, we interviewed 46 mothers, in a period of 5 months. Mothers were include if they could do the routine care of the newborn, their scores were less than 25 in participation checklist, the ability to read and write, not affected a physical or mental illness. Among the mothers who were interviewed 12 people were excluded from the study because: neonate mortality, discharge from the NICU unit and lack of personal interest. Finally the study was performed with 34 subjects Results paired t-test showed significant difference in the participation score of mothers in the care of neonates after the intervention than before (P= 0.000). Also, there is a significant difference among all the health belief model constructs, after the intervention than before. (P <0.05). Conclusion Based on the results of this study, it is suggested; health education models can be used in clinical research nursing and empowerment programs related to individuals, families and other groups.
Iranian Journal of Neonatology
Mashhad University of Medical Sciences
2251-7510
4
v.
2
no.
2013
16
20
https://ijn.mums.ac.ir/article_1077_9ce19544aa3e601ecc35ba7af229bb3c.pdf
dx.doi.org/10.22038/ijn.2013.1077
Etiologies and Antibiotic Resistance Patterns in Infants With Urinary Tract Infections Hospitalized in Children Medical Center, Rasht, Iran
Fatemeh
Aghamahdi
Department of pediatrics, Medicine Faculty, Guilan University of medical science, Rasht, Iran
author
Houman
Hashemian
Department of pediatrics, Medicine Faculty, Guilan University of medical science, Rasht, Iran
author
Masumeh
Shafiei
Department of pediatrics, Medicine Faculty, Guilan University of medical science, Rasht, Iran
author
Zahra
Akbarian
Department of pediatrics, Medicine Faculty, Guilan University of medical science, Rasht, Iran
author
Maryam
Rostam Nejad
Department of pediatrics, Medicine Faculty, Guilan University of medical science, Rasht, Iran
author
Morteza
Fallah Karkan
Department of pediatrics, Medicine Faculty, Guilan University of medical science, Rasht, Iran
author
text
article
2013
eng
Introduction Urinary tract infection (UTI) is one of the most common infections in childhood. Appropriate treatment of UTI requires to knowledge about antibiotic resistance patterns of common uropathogens. The aim of this study was to determine demographic, symptoms, signs and antibiotic resistance pattern in admitted infants with clinically diagnosis of UTI in 17 Shahrivar Hospital of Rasht Materials and Methods This retrospective study was performed on 77 patients less than 2 years old from March 2006 to march 2011. They were admitted with clinical diagnosis of UTI and posilive. Urine cultures data (demographic, symptoms, signs and the results of urine analysis and urine cultures) were analyzed by SPSS and Chi-squart Results From 77 patients, 53.2% were female, with mean age of 8.07 ± 6.84 months. The most common symptom was fever(48.1%) vomiting and diarrhea were second and third prevalent symptom. 18.1% had leukocytosis and CRP was positive in 67.3%. Leukocyturia in 58.4% and hematuria in 19.5% of them were seen. The most common agent was E coli (59.7%) followed by Klebsiella and Enterobacter (14.3%) and Coagulase negative Staphylococcus (5.2%). Isolated pathogens were resistance to ampicillin (94.1%), amoxicillin (88.9%), cefalexin (70.5%), co-trimoxazole (66.7%), cefixime (75%). This antibiotic resistance was less for nalidixic acid (37%), ceftriaxone (20%), aminoglycosids (24.6%), nitrofurantoin (22.4%) and ciprofloxacin (14.8%). Conclusion Ecoli was the most frequent pathogen in our study. Resistance to all antibiotics used to treat UTI was common. Due to the low sensitivity of ampicillin, amoxicillin, cefalexin and co-trimoxazole, use of them is not recommended for the treatment of UTI. It seems that the best choices include ceftriaxone, aminoglycosids, nalidixic acid, and nitrofurantoin
Iranian Journal of Neonatology
Mashhad University of Medical Sciences
2251-7510
4
v.
2
no.
2013
21
25
https://ijn.mums.ac.ir/article_1078_aecdc4091390520d2ffaa696e0e4036c.pdf
dx.doi.org/10.22038/ijn.2013.1078
Survey on correlation between unplan pregnancy and low birth weight in new infants
Reza
Saeedi
associate of pediatric department –assistant director of health chancellery, Mashhad University of Medical Sciences, Mashhad, Iran
author
Mohammad
Ahmadian
Mohammad ahmadian- MD –MPH- manager of health population, family, nutrition and School of Health, Mashhad University of Medical Sciences, Mashhad, Iran
author
Mohammad
bolbolian ghalibaf
Mohammad bolbolian ghalibaf- assistant of statistic department- hakim Sabzevri University
author
Mitra
hashemian
Mitra hashemian- manage of productivity health, of health chancellery, Mashhad University of Medical Sciences, Mashhad, Iran
author
text
article
2013
eng
Introduction weight in delivery is simplest and current health indication for assessment infant statues in each country. Purpose of this study is assessment correlation to unplan pregnancy and low birth weight in new infants also some key factors influencing on low birth weight. Materials and Methods in this study 838 pregnant mothers in two group wanted and unwanted performed. This study is descriptive and analytically based on cohort study. Sample size was all mothers who refer to nine health clinics in mashhad province in 2012. Questionnaire completed based on interview to mothers and observe health records. For analyzing data used chi-square and T-student tests. Results finding showed that in wanted group ( n=602) and unwanted (n=236) , 10.3 % of infants are LWB, in wanted group 11% and unwanted group 8.5% reported however there was no significant relation between two groups. There was a significant relationship between two groups in number of pregnancy and time of first reference to health clinic and duration between recent and previous visit (p=0.05). T-STUDENT test showed that thre is a signigicant relationship between the mean of mothers age and number of pregnancy in two groups(p=0.05) also chi square test showed that some factors like lodging of mother, mothers job, mothers education and her husband education had significant difference between two groups of wanted and unwanted pregnancy . Some factors like unwanted pregnancy and hypertension, diabetes, smoking, separately had studied but the result showed that only drug abuse had a significant effect on LBW , however in mothers with drug abuse 40% and mothers without drugabuse 9.7% cause to LWB. Conclusion considering the importance of birth weight in health of infants and advers of unplanned pregnancy on it specialy in cases with high risk behaviours, pre-pregnancy caring and increase knowledge of mothersabout the importance of this cares are necessary.
Iranian Journal of Neonatology
Mashhad University of Medical Sciences
2251-7510
4
v.
2
no.
2013
26
33
https://ijn.mums.ac.ir/article_1079_74c04c5d011f59d26e00be70d78db484.pdf
dx.doi.org/10.22038/ijn.2013.1079
Tuberous sclerosis with Cardiac Tumor in fetus with Diabetic Mother
Seyed Hasan
Voshtani
Assistant professor, Pediatric cardiology department- Heshmat Cardiology Hospital, Rasht, Iran
author
Hannan
Ebrahimi
Medical Student, Student Research Committee, Giulan University of Medical
Science, Rasht, Iran
author
Sina
Khajeh Jahromi
Medical Student, Student Research Committee, Giulan University of Medical Science, Rasht, Iran
author
text
article
2013
eng
Introduction A heart tumor in children is rare and the most primary tumor of the heart is rhabdomyoma. We report a case of cardiac mass diagnosed at 32th weeks of pregnancy while the mother had gestational diabetes Mellitus. Serial echocardiography revealed regression of the tumor; then follow up of the patient confirmed tuberous sclerosis.
Iranian Journal of Neonatology
Mashhad University of Medical Sciences
2251-7510
4
v.
2
no.
2013
34
37
https://ijn.mums.ac.ir/article_1080_fbd627e432d27c9465841d06d28b5a78.pdf
dx.doi.org/10.22038/ijn.2013.1080
A case report of hypervitaminosis D in 2 months old infant
Ahmadshah
farhat
Assistant professor of Neonatology Neonatal Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
author
Ashraf
Mohamadzadeh
Neonatal Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
author
Said Javad
Sayedi
Department of pediatric , Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
author
zeinab
Nourbakhsh
Pediatric resident of Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
author
Mehrieh
Rezaei
General physisian, Mashhad University of Medical Sciences, Mashhad, Iran
author
text
article
2013
eng
Introduction Vit D level is low in human milk (20-60 IU/Lit) thus dialy supplement of 400 Vit D is advised since birth for all infants. On the other hand upper limit dose for long term Vit D intake is 1000 IU/day for children less than one year of age. Excessive Vit D more than upper limit by physicians or parents can cause hypervitaminoseD. We report a rare case of hypervitaminose D in two months old infant.
Iranian Journal of Neonatology
Mashhad University of Medical Sciences
2251-7510
4
v.
2
no.
2013
38
40
https://ijn.mums.ac.ir/article_1081_6d34a76f9d4b7faf0c0196ed04b0b211.pdf
dx.doi.org/10.22038/ijn.2013.1081